J. Miguel Sanches

Associate Professor (Habilitation)
Coordinator for Biomedical Engineering
Bioengineering Department (DBE)
Instituto Superior Técnico, Universidade de Lisboa
IEEE senior member
Institute for Systems and Robotics

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Research Interests


  • Signal and Systems in Bioengineering (SSB)
  • Instrumentation and Acquisition of Signals in Bioengineering (IASB)

Selected publications

  1. Carlos J. C. Rodrigues, João M. Sanches and Carla C. C. R. de Carvalho, Determining transaminase activity in bacterial libraries by time- lapse imaging, Chemical Communications, 2019. doi: 10.1039/C9CC07507K

  2. Figueiredo J, Rodrigues I, Ribeiro J, Fernandes MS, Melo S, Sousa B, Paredes J, Seruca R, Sanches JM, Geometric compensation applied to image analysis of cell populations with morphological variability: a new role for a classical concept, Scientific Reports (Nature),  2018 Jul 6;8(1):10266. doi: 10.1038/s41598-018-28570-z.

  3. Anabela Ferro, Tânia Mestre, Patrícia Carneiro, Ivan Sahumbaiev, Raquel Seruca and João M. Sanches,
    Blue intensity matters for cell cycle profiling in fluorescence DAPI-stained images, Laboratory Investigation (Nature), 6 March 2017.

  4. Mestre T, Figueiredo J, Ribeiro AS, Paredes J, Seruca R and Sanches JM, Quantification of topological features in cell meshes to explore E-cadherin dysfunction, Scientific Reports (Nature). 2016 May 6;6:25101 , doi: 10.1038/srep25101.

  5. Afonso, M.V.; Miguel Sanches, J., Blind Inpainting using L0 and Total Variation Regularization,
    Image Processing, IEEE Transactions on , Vol. 24, No. 7,  July 2015, doi: 10.1109/TIP.2015.2417505 (URL).

  6. David Afonso, José Seabra, Luís Pedro, J. Fernandes e Fernandes and J. Miguel Sanches, An Ultrasonographic Risk Score For Detecting Symptomatic Carotid Atherosclerotic Plaques,
    Biomedical and Health Informatics, IEEE Journal of , vol.19, no.4, pp.1505,1513, July 2015
    doi: 10.1109/JBHI.2014.2359236.

  7. Domingues, A; Paiva, T.; Sanches, J.M., Hypnogram and Sleep Parameter Computation From Activity and Cardiovascular Data, Biomedical Engineering, IEEE Transactions on , vol.61, no.6, pp.1711,1719, June 2014
    doi: 10.1109/TBME.2014.2301462.

  8. Ribeiro, R.T.; Marinho, R.T.; Sanches, J.M., Classification and Staging of Chronic Liver Disease From Multimodal Data, Biomedical Engineering, IEEE Transactions on Biomedical Engineering , vol.60, no.5, pp.1336,1344, May 2013.
    doi: 10.1109/TBME.2012.2235438.

  9. Seabra, J.C.; Ciompi, F.; Pujol, O.; Mauri, J.; Radeva, P.; Sanches, J., Rayleigh Mixture Model for Plaque Characterization in Intravascular Ultrasound, Biomedical Engineering, IEEE Transactions on , vol.58, no.5, pp.1314-1324, May 2011.

  10. Isabel Rodrigues and João Sanches, Convex Total Variation Denoising of Poisson Fluorescence Confocal Images with anisotropic filtering, IEEE TRANSACTIONS ON IMAGE PROCESSING, VOL. 20, NO. 1, JANUARY 2011.

  11. Sanches, J. M.   Nascimento, J. C.Marques, J.S.,Medical Image Noise Reduction Using the Sylvester–Lyapunov Equation, IEEE Transactions on Image Processing, Volume: 17,  Issue: 9, pp.1522-1539, September. 2008.


Instituto Superior Técnico (Alameda)
Torre Norte, 6º Piso, Sala 6.09
Av. Rovisco Pais, 1049-001 Lisboa

email: jmrs(at)

Phone: +351 81 8418 195 (Ext: 2195)